| 摘要 |
<p>A metal surface carries a coating comprising spacer units, e.g. protein molecules, to which haptens are linked. These metal surfaces are useful for assays, e.g. in which dissolved haptens in a sample compete with immobilised haptens for binding to antibodies. The coated metal surfaces are adapted for use in surface plasmon resonance (SPR) techniques. Also included are immunoassays in which antibodies are immobilised on the metal surface with hapten conjugates reversibly bound to them, displacement of conjugate, as a result of addition of a sample containing the hapten, being monitored by SPR.</p> |
