| 摘要 |
<p>Diagnostic compositions comprising conjugates of ligands or antibodies or hybrids of antibodies reactive both to specific substances (e.g. antigens) on one hand and to erythrocytes on the other hand, which will induce an aggregation of erythrocytes in presence of the said specific substance in a clinically significant amount for detection and/or quantification of the said specified substance in blood, plasma, serum or other body liquids, and the use of compositions comprising mixtures of conjugates or hybrids of antibodies, reactive to different antigenic determinants on erythrocytes and/or different antigenic determinants on the said specific substance in order to increase the sensitivity of the compositions for detection and/or quantification of the said specific substance in blood, plasma, serum or other body liquids, and the use of such compositions in combinations with antibodies reactive to the said specific substances, but not to erythrocytes, in order to adjust the sensitivity of the detection and/or quantification of the said specified antigenic substance in blood, plasma, serum or other body liquids. Such antibodies, conjugates and/or hybrids may be of monoclonal or polyclonal origin. This invention may be used in veterian and human medicine for diagnosis.</p> |
