| 摘要 |
Aminoborane esters of formula R1R2R3NBH2COOR4, wherein R4 is C1-C8 alkyl, C1-C8 haloalkyl, phenyl, benzyl or cholesteryl and
(a) each of R1, R2, and R3, which may be the same or different, is hydrogen, C1-C8 alkyl, C1-C8 haloalkyl, phenyl or benzyl with the proviso that at least one of R1, R2, and R3 is hydrogen, or
(b) each of R1, R2, and R3 is methyl with the proviso that R4 is also methyl are useful in the lowering of serum cholesterol or triglyceride levels. These esters and related compounds can be prepared by esterifying the amine carboxyborane, preferably using a chloroformate in solution in the presence of a trialkylamine. |
