| 摘要 |
Preparation of compounds where R = alkyl (1-4C) alkenyl, or alkynyl. A = lower alkanoyl. - The reaction is effected as follows: - (a) (II) is reacted with an alkylating, alkenylating, or alkynylating agent by conventional means, pref. with a halide in the presence of a weak base, such as an alkali metal carbonate, in an inert solvent. - (b) is effected in aqueous or alcoholic media in the presence of a catalytic amount of base, or it may be effected by means of anion exchange resin, e.g. Amberlite IRA-400. - (c) is effected by treatment of (IV) with an aqueous alkaline hypohalite - (d) is effected by the condensation of (V) with a N-acylsulphanilyl chloride in the presence of an acid binding agent, such as pyridine. The deacylation stage (e) is effected by conventional acid or base hydrolysis, pref. using 6N HCl. - Anticoccidials and antibacterials.
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