发明名称 |
WERKWIJZE VOOR HET BEREIDEN VAN EEN ANTIBIOTICUM, WERKWIJZE VOOR DE BEREIDING VAN EEN, EEN DERGELIJK ANTIBIOTICUM BEVATTEND VETERINAIR PREPARAAT EN BEREIDING VAN EEN DERGELIJK ANTIBIOTICUM BEVATTEND DIERVOEDER. |
摘要 |
The novel antibiotic A-28086 complex containing the factors A, B and D is produced by culturing Streptomyces aureofaciens NRRL 5758 or Streptomyces aureofaciens NRRL 8092 in a culture medium, which contains assimilable sources for carbohydrate, nitrogen and inorganic salts, in submerged aerobic fermentation conditions until these organisms have produced a significant amount of antibiotic activity in the culture medium. The antibiotic is then separated off from the culture medium. The novel antibiotic can be dissociated into the factors A, B and D. These can be converted into the corresponding physiologically tolerated salts. The novel antibiotic can likewise be converted into C2-C6-acyl esters. The novel antibiotic A-28086 complex, the factors A, B and D, the physiologically tolerated salts thereof and also C2-C6-acyl esters thereof are used to increase the feed intake of ruminants. They can additionally be used for the prevention or treatment of coccidiosis in poultry. |
申请公布号 |
NL184575(C) |
申请公布日期 |
1989.09.01 |
申请号 |
NL19750006920 |
申请日期 |
1975.06.10 |
申请人 |
ELI LILLY AND COMPANY TE INDIANAPOLIS, INDIANA, VER. ST. V. AM. |
发明人 |
|
分类号 |
A01N63/02;A23K20/195;A61K31/325;A61K31/35;A61K35/66;A61K35/74;A61P31/04;C07D493/20;C07H19/01;C12P1/06;C12P17/18;C12R1/485 |
主分类号 |
A01N63/02 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|