NEW SUBSTITUTED DICARBOXYLIC ACID-BIS(3,5-DICARBAMOYL-2,4,6-TRIIODOANILIDES),PROCESS FOR THEIR PRODUCTION AS WELL AS X-RAY CONTRAST MEDIA CONTAINING THEM

摘要

Novel substituted dicarboxylic acid bis(3,5-dicarbamoyl- 2,4,6-triiodoanilides) of the general formula …… in which… R<1> denotes a hydrogen atom, a C1-C4-alkyl radical or R<2>,… R<2> denotes a straight-chain or branched-chain C2-C8-mono- or polyhydroxyalkyl radical,… R<3> denotes a hydrogen atom, a C1-C4-alkyl radical or R<2>,… R<4> denotes a hydrogen atom or a C1-C4-alkyl radical and… n = 1 or 2. …Owing to their good pharmacological and physicochemical properties, the novel non-ionic compounds of the formula I are outstandingly suitable as radio-opaque substances in X-ray contrast agents for use in all application areas of X-ray contrast agents.