发明名称 TERT-BUTYL PHENYL COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS
摘要 The present invention involves compounds having the structure: <CHEM> (a) -A<1> is selected from the group consisting of -OH, -H, and -O2CR; (b) -A<2> is selected from the group consisting of unsubstituted or substituted, saturated or unsaturated, straight, branched and cyclic alkyl having from 1 to about 10 carbon atoms; (c) -A<3> is selected from -C(CH3)3, -Si(CH3)3, and -CF3; and (d)-Y is selected from certain low molecular weight alkyl chains which terminate in specific unsaturated functional groups: -C IDENTICAL CH, - @-=CH2, -@=C=CH2 and aldehydes in the form of their acetals; pharmaceutical compositions comprising such compounds; and methods for treating inflammation by administering such compounds.
申请公布号 ZA8808726(B) 申请公布日期 1989.08.30
申请号 ZA19880008726 申请日期 1988.11.22
申请人 THE PROCTER & GAMBLE COMPANY 发明人 MAURICE EDWARDS LOOMANS;RANDALL STRYKER MATTHEWS;JOSEPH ARTHUR MILLER
分类号 A61K31/015;A61K31/05;A61K31/085;A61K31/12;A61K31/135;A61K31/165;A61K31/22;A61K31/335;A61K31/357;A61K31/695;A61P7/00;A61P9/10;A61P15/04;A61P25/04;A61P29/00;A61P37/00;C07C1/00;C07C15/42;C07C17/00;C07C25/24;C07C39/18;C07C39/24;C07C41/00;C07C43/20;C07C43/303;C07C45/00;C07C45/45;C07C45/46;C07C45/67;C07C45/68;C07C49/248;C07C49/255;C07C49/835;C07C49/84;C07C59/52;C07C59/64;C07C59/84;C07C59/90;C07C67/00;C07C69/035;C07C209/00;C07C211/28;C07C215/48;C07C219/28;C07C225/06;C07C233/18;C07C233/31;C07C321/20;C07C323/16;C07C323/22;C07C323/29;C07C323/40;C07C323/56;C07D317/26;C07D327/04;C07D339/06 主分类号 A61K31/015
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