摘要 |
The present invention involves compounds having the structure: <CHEM> (a) -A<1> is selected from the group consisting of -OH, -H, and -O2CR; (b) -A<2> is selected from the group consisting of unsubstituted or substituted, saturated or unsaturated, straight, branched and cyclic alkyl having from 1 to about 10 carbon atoms; (c) -A<3> is selected from -C(CH3)3, -Si(CH3)3, and -CF3; and (d)-Y is selected from certain low molecular weight alkyl chains which terminate in specific unsaturated functional groups: -C IDENTICAL CH, - @-=CH2, -@=C=CH2 and aldehydes in the form of their acetals; pharmaceutical compositions comprising such compounds; and methods for treating inflammation by administering such compounds. |