| 摘要 |
<p>The present invention provides novel compounds as well as known compounds which have been discovered to have important hair growth promoting properties, but which have much less toxicity and antihypertensive properties as compared to minoxidil and can be used at higher concentrations having formula (I) including active isomers, precursors and metabolites thereof, wherein B is a disubstituted heterocyclic N-oxide moiety selected from the group consisting of pyridines, pyrimidines, and triazines, and Dn forms a homocyclic carbon ring or a heterocyclic ring of n members in addition to the para carbon atom of the piperidinyl ring, wherein n equals 2 to 8, and at least two of the ring members D are carbon atoms and the reminder of the ring members, if any, are selected from the group consisting of oxygen, nitrogen, carbon and sulfur, the ring being saturated or unsaturated, and the carbon and nitrogen ring members being substituted or unsubstituted, with the possibility that the substituents, if any, form an additional ring.</p> |
