PREVENTIVE OF CONSTRICTION AND ACUTE CEREBRAL ISCHEMIA

摘要

PURPOSE: To obtain preventive for infarctus and acute cerebral ischemia by including trazodone or its acid-addition salt as an active ingredient. CONSTITUTION: Infarctus and acute cerebral ischemia is prevented by administering a pharmaceutical composition containing trazodone or its acid addition salt to a patient in a dangerous state. The pharmaceutical composition is preferably administered as a controlled release pharmaceutical composition capable of releasing 1-10mg/h, preferably 1.5-7mg/h trazodone calculated in terms of an in vivo base.