NUCLEAR FACTORS ASSOCIATED WITH TRANSCRIPTIONAL REGULATION
摘要
Constitutive and tissue-specific protein factors which bind to transcriptional regulatory elements of Ig genes (promoter and enhancer) are described. The factors were identified and isolated by an improved assay for protein-DNA binding. Genes encoding factors which positively regulate transcription can be isolated and employed to enhance transcription of Ig genes.
申请公布号
WO8907614(A1)
申请公布日期
1989.08.24
申请号
WO1989US00553
申请日期
1989.02.10
申请人
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH