| 摘要 |
The present invention discloses a DNA transfer vector comprising two or more deoxynucleotide sequences coding for different antigenic materials linked together in phase with one another. The present invention further discloses the expression of said deoxynucleotide sequences either directly or as a fusion protein with the product of a procaryotic gene. The resulting expression product is then either a fusion protein comprising two or more antigenic materials or a fusion protein comprising a part of a procaryotic protein and two or more antigenic materials. These fusion products are capable of eliciting the formation of multivalent antibodies which are cross-reactive with any and all of the native antigenic material. A vaccine is also described utilizing these fusion products.
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