发明名称 DI OR TRIPEPTIDE RENNIN INHIBITOR CONTAINING LACTAM STEREOSCOPIC PRESCRIPTION IN ACHPA
摘要 Enzyme di- or tripeptides of the formula: <CHEM> and analogs thereof which inhibit renin and are useful for treating various forms of renin-associated hypertension, hyperaldosteronism and congestive heart failure; compositions containing these renin-inhibitory peptides, optionally with other antihypertensive agents; and methods of treating hypertension, hyperaldosteronism or congestive heart failure or of establishing renin as a causative factor in these problems which employ these novel peptides.
申请公布号 JPH01207300(A) 申请公布日期 1989.08.21
申请号 JP19880259291 申请日期 1988.10.14
申请人 MERCK & CO INC 发明人 PEETAA DEE UIRIAMUSU;DANIERU EFU BUEEBAA;UIRIAMU JIEE GURIINRII;JIYAN TEN BUREEKE
分类号 C12N9/99;A61K38/55;A61P9/00;A61P29/00;C07D207/267;C07D207/27;C07D207/28;C07D233/54;C07D401/04;C07D403/12;C07D453/02;C07K5/02;C07K5/06;C07K14/81 主分类号 C12N9/99
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