发明名称 PHOTOSTABILIZATION OF MOLSIDOMINE
摘要 1. Claims for the Contracting States : BE, CH, DE, FR, GB, IT, LI, NL Photostabilised mixture of molsidomine, one or several photostabilisers, and, if appropriate, further mixing components, characterised in that the photostabilisers are compounds of the general formula I see diagramm : EP0147811,P13,F4 wherein Y denotes a hydroxyl group, alkoxy having 1 or 2 C atoms or beta-hydroxyethoxy and Z denotes a group of the formula see diagramm : EP0147811,P13,F5 or Y and Z together denote a structural element of the formula II or III see diagramm : EP0147811,P13,F6 see diagramm : EP0147811,P13,F7 in which the free oxygen valency is attached in the Y-position and the free carbon valency is attached in the Z-position and R**1 denotes hydrogen or a radical G, R**2 denotes hydrogen, alkyl having 1 or 2 C atoms or beta-hydroxyethyl, R**3 denotes hydrogen, alkyl having 1 or 2 C atoms or beta-hydroxyethyl, R**4 denotes hydrogen, alkyl having 1 or 2 C atoms, beta-hydroxyethyl or a radical G and G is the radical of a monosaccharide or disaccharide, or esters of these compounds with pharmacologically acceptable acids and also, if appropriate, a salt thereof with pharmacologically acceptable bases. 1. Claims for the Contracting State : AT Process for photostabilising molsidomine and mixtures of molsidomine with mixing components, characterised in that there are added, respectively to the molsidomine and its mixtures, as photostabilisers, one or several compounds of the general formula I see diagramm : EP0147811,P15,F1 wherein Y denotes a hydroxyl group, alkoxy having 1 or 2 C atoms or beta-hydroxyethoxy and Z denotes a group of the formula see diagramm : EP0147811,P15,F2 or Y and Z together denote a structural element of the formula II or III see diagramm : EP0147811,P15,F3 see diagramm : EP0147811,P15,F4 in which the free oxygen valency is attached in the Y-position and the free carbon valency is attached in the Z-position and R**1 denotes hydrogen or a radical G, R**2 denotes hydrogen, alkyl having 1 or 2 C atoms or beta-hydroxyethyl, R**3 denotes hydrogen, alkyl having 1 or 2 C atoms or beta-hydroxyethyl, R**4 denotes hydrogen, alkyl having 1 or 2 C atoms, beta-hydroxyethyl or a radical G and G is the radical of a monosaccharide or disaccharide, or esters of these compounds with pharmacologically acceptable acids and also, if appropriate, a salt thereof with pharmacologically acceptable bases.
申请公布号 EP0147811(B1) 申请公布日期 1989.08.16
申请号 EP19840116004 申请日期 1984.12.20
申请人 CASSELLA AKTIENGESELLSCHAFT 发明人 VOEGELE, DIETER;LAUDENBACH, PETRA
分类号 C07D271/04;A61K31/535;A61K47/00;A61K47/10;A61K47/22 主分类号 C07D271/04
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