Process for preparing optically active 2-halo-1-phenyl ethanol

摘要

A process for preparing optically active 2-halo-1-phenyl ethanol having the general formula [I*]: [I*] wherein X is a halogen atom, by asymmetrically reducing 2-halo-acetophenone having the general formula [II]: [II] wherein X is as above, to give optically active 2-halo-1-phenyl ethanol, (R)-form or (S)-form, employing the microorganism. +TR According to the present invention, optically active 2-halo-1-phenyl ethanol can be prepared with a good optical purity and yield in a simple process.