| 发明名称 |
Quinuclidyl benzoxepins as 5-HT3antagonists |
| 摘要 |
Certain specific substituted 9-N-(1-azabicyclo-[2.2.2.]octan-3-yl)carboxamido-2,3,4,5-tetrahydro-1- benzoxepins and their valuable use as 5-HT3 antagonists having CNS and gastric prokinetic acticity and void of any significant D2 receptor binding properties are disclosed. Methods for their preparation also are described.
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| 申请公布号 |
US4857517(A) |
申请公布日期 |
1989.08.15 |
| 申请号 |
US19880152112 |
申请日期 |
1988.02.04 |
| 申请人 |
RORER PHARMACEUTICAL CORPORATION |
发明人 |
YOUSSEFYEH, RAYMOND;KLEIN, SCOTT I.;CAMPBELL, HENRY F.;KUHLA, DONALD E. |
| 分类号 |
C07D453/02 |
主分类号 |
C07D453/02 |
| 代理机构 |
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代理人 |
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