摘要 |
A biosensor includes an optically dense body provided with a coating sensitized to a specific assay species, and an input and output coupling structure. Light signal response is enhanced by incorporating a partially reflecting, partially transmitting medium between the coupling structure and the optically dense body having a lower refractive index. The thickness of such medium is chosen so that light may be coupled by frustrated total internal reflection and to enable the medium to serve as a resonant mirror.
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