| 摘要 |
There are disclosed compounds of the formula <IMAGE> wherein R1 and R2 are each, independently, hydrogen, lower alkyl or phenyl; or R1 and R2 taken together represent -(CH2)4-or <IMAGE> where the dotted line represents an optional double bond; R3 is hydrogen, lower alkyl, lower alkoxy or halo; R4 is pyridinyl, pyrimidinyl, pyrazinyl, benzyl, phenyl or phenyl substituted by lower alkyl, lower alkoxy, or halo; Z is -SO2-or <IMAGE> where R5 is hydrogen or lower alkyl; m is 0-4; n is 0-2; and the pharmaceutically acceptable salts thereof, and their use as anti-inflammatory agents.
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