摘要 |
<p>A compound is provided herein having the formula: (I) wherein R1 is halogen, an unsubstituted hydrocarbyl group, or a hydrocarbyl group substituted with hydroxyl, amino or carbonyl groups and which can be interrupted in the carbon atom chain by O, S or N: wherein R2, R6 and R7, which may be the same or different, each represents hydrogen. an unsubstituted hydrocarbyl group, or a hydrocarbyl group substituted with hydroxyl, amino or carbonyl groups and can be interrupted in the carbon atom chain by O, S or N, or R6 and R7 taken together may represent a hetero group having one or more hetero atoms; wherein R3 and R4, which may be the same or different, each represents an unsubstituted hydrocarbyl group, or a hydrocarbyl group substituted with hydroxyl, amino or carbonyl groups and can be interrupted in the carbon atom chain by O, S or N, or wherein R3 and R4 taken together may represent an alkylene group or a hetero group having one or more hetero atoms: and wherein R5 is hydrogen, an unubstituted hydrocarbyl group or a hydrocarbyl group - Page 2 substituted with hydroxyl, amino or carbonyl groups and can be interrupted in the carbon atom chain by O, S or N, halogen or a free or protected hydroxy group, or a pharmaceutically acceptable salt thereof. The compounds have antiaggregating properties and some of them also have antitumor and antimetastatic activity.</p> |