摘要 |
<p>Novel 2,2-disubstituted glycerol compounds are disclosed for use as anti-allergic and anti-inflammatory compounds. The compounds are antagonists of platelet activating factor (''PAF''). Also disclosed are methods of synthesizing and using the compounds of the invention as well as pharmaceutical compositions thereof. The compounds have formula (I), wherein R?1, R2, R3, and R4¿ are as defined in the specification.</p> |