Probe for pneumocystis carinii.

摘要

The invention provides DNA probes which hybridize to the DNA of Pneumocystis carinii but not to mammalian DNA, and which form the basis of an in vitro diagnostic test for viable P.carinii organisms in respiratory secretion or even sputum. The probes are made by recombinant DNA technology from infected rat lung tissue. Preferred in the plasmid designated pAZ112, derived from the vector pUC13, having a size of approximately 9.8 kbp and which has been partly sequenced.