发明名称 Polycyclicamine with psychotropic activity
摘要 There are disclosed compounds of the formula <IMAGE> wherein R represents <IMAGE> where X is lower alkylene, vinylene or O; Y is lower alkylene or vinylene; the dotted line represents an optional double bond; m is 1-3; n is 2-4; A is phenyl, benzoyl, pyridinyl, quinolinyl or quinoxalinyl, or any of the foregoing substituted with lower alkyl, lower alkoxy, halo, cyano, nitro or trifluoromethyl; or when m is>1, A represents the grouping <IMAGE> where B is phenyl, pyrimidinyl, pyridinyl or pyrazinyl, or any of the foregoing substituted with lower alkyl, lower alkoxy, halo, cyano, nitro or trifluoromethyl, with the proviso that where R is <IMAGE> A is other than unsubstituted or substituted benzoyl or pyridinyl; and the pharmacologically acceptable salts thereof and their use as antipsychotic/anxiolytic and antidepressant agents and in the treatment of sexual dysfunction and having a low liability for extrapyramidal side effects.
申请公布号 US4855430(A) 申请公布日期 1989.08.08
申请号 US19870119530 申请日期 1987.11.12
申请人 AMERICAN HOME PRODUCTS CORPORATION 发明人 ABOU-GHARBIA, MAGID A.;PATEL, USHA R.
分类号 C07D209/56;A61K31/395;A61K31/40;A61K31/403;A61K31/44;A61K31/4427;A61K31/47;A61K31/495;A61K31/555;A61P25/00;A61P25/20;A61P25/24;A61P25/26;C07D209/72;C07D209/94;C07D213/38;C07D223/32;C07D239/42;C07D239/47;C07D241/20;C07D241/26;C07D241/44;C07D295/04;C07D401/06;C07D403/06 主分类号 C07D209/56
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