发明名称 |
Scattered total internal reflectance immunoassay system. |
摘要 |
<p>A new immunoassay system is provided for the detection of ligands or ligand binding partners in solution in a heterogeneous format. The invention relies upon the detection of back scattered light from an evanescent wave disturbed by the presence of a colloidal gold label brought to the interface by an immunological reaction. The evanescent wave existing at the interface in turn is the result of a totally internally reflected incident light wave. Placement of the detector at a back angle above the critical angle insures a superior signal-to-noise ratio.</p> |
申请公布号 |
EP0326375(A2) |
申请公布日期 |
1989.08.02 |
申请号 |
EP19890300737 |
申请日期 |
1989.01.26 |
申请人 |
ORTHO DIAGNOSTIC SYSTEMS INC. |
发明人 |
SCHUTT, ERNEST G.;HANSEN, WILLIAM P.;MEYER, RAYMOND E.;DONDERO, RICHARD S.;HOVORKA, GEORGE B. |
分类号 |
G01N21/27;G01N21/47;G01N21/55;G01N33/543;G01N33/553;G01N33/557;G01N33/58 |
主分类号 |
G01N21/27 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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