发明名称 BICYKLISKA FOERENINGAR
摘要 Novel compounds of the formula <IMAGE> I wherein B represents a methylene, ethylene or vinylene group, R1 represents a hydrogen atom or an alkyl, aralkyl, amino-alkyl, mono-alkylamino-alkyl, dialkylaminoalkyl, acylamino-alkyl, phthalimido-alkyl, alkoxycarbonylamino-alkyl, aryloxycarbonylamino-alkyl, aralkoxycarbonylamino-alkyl, alkylaminocarbonylamino-alkyl, arylaminocarbonylamino-alkyl, aralkylaminocarbonylamino-alkyl, alkylsulphonylamino-alkyl or arylsulphonylamino-alkyl group, R2 represents a carboxyl, alkoxycarbonyl or aralkoxycarbonyl group or a group of the formula <IMAGE> R3 represents a carboxyl, alkoxycarbonyl or aralkoxycarbonyl group, R4 and R5 each represent a hydrogen atom or R4 and R5 together represent an oxo group, R6 and R7 each represent a hydrogen atom or an alkyl or aralkyl group or R6 and R7 together with the nitrogen atom to which they are attached represent a 5-membered or 6-membered heteromonocyclic ring which may contain a further nitrogen atom or an oxygen or sulphur atom, and n stands for zero, 1 or 2, and pharmaceutically acceptable salts thereof have antihypertensive activity and can be used as medicaments in the form of pharmaceutical preparations.
申请公布号 FI831661(L) 申请公布日期 1983.11.13
申请号 FI19830001661 申请日期 1983.05.12
申请人 F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT 发明人 ATTWOOD, MICHAEL RICHARD;HASSALL, CEDRIC HERBERT;LAMBERT, ROBERT WILSON;LAWTON, GEOFFREY;REDSHAW, SALLY
分类号 C07D209/48;C07D231/04;C07D237/04;C07D403/06;C07D487/04;C07F9/38;C07F9/40;C07F9/6509;C07F9/6561;C07K5/078 主分类号 C07D209/48
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