摘要 |
NEW MATERIAL:To cyclohexanecarboxylic acid derivative of formulaI(R is 2-10C alkyl). EXAMPLE:cis-1-n-Butyl-3-hydroxycyclohexanecarboxylic acid. USE:Drugs having remarkable pharmacological effects such as antitumor activity, antiallergic activity, hepatic function improving activity, antirheumatic activity, etc. and no side effect. PROCESS:The compound of formulaIcan be prepared by hydrolyzing the compound of formula II in an alkali (e.g. NaOH, KOH, etc.) or an acid (e.g. hydrochloric acid, sulfuric acid, etc.). |