A PROCESS FOR PASTEURIZATION OF AQUEOUS SOLUTIONS OF FACTOR VIII

摘要

In a process for pasteurization of aqueous solutions of Factor VIII, the solution is heated to a temperature of 55-65 DEG C for a period of time of 5-15 hours in the presence of saccharide or a sugar alcohol as well as 1-4, preferably 1.5-2.5 IU of heparin per g of solution. The heparin has a stabilizing effect so that degradation of Factor VIII is avoided or limited.