METHODS FOR PREVENTING AND TREATING THROMBOSIS;AND SURGICAL IMPLANT HAVING REDUCED PLATELET DEPOSITION CHARACTERISTICS

摘要

In order to improve the surface properties of small caliber vascular grafts or other surgical implants, Forskolin (or a derivative thereof) which is a power cAMP stimulating agent, is applied to the thrombogenic surfaces of the graft/implant. Forskolin as thus used is a potent antiplatelet agent significantly lowering platelet deposition on the implant.