发明名称 Use of 1,4-disubstituted-piperidinyl compounds in the manufacture of a medicament for the treatment of insomnia.
摘要 <p>The present invention pertains to the use of 1,4-disubstituted-piperidinyl compounds in the treatment of insomnia. Said compounds have the following general formula: &lt;CHEM&gt; wherein: each of R&lt;1&gt;&lt;,&gt; R&lt;2&gt;&lt;,&gt; R&lt;3&gt;&lt;,&gt; and R&lt;4&gt; is independently selected from the group consisting of hydrogen a C1-6 alkyl group halogen, trifluoromethyl, hydroxyy, a C1-6 alkoxy group, or an amino group; n is 2, 3, or 4; and the pharmaceutically acceptable acid addition salts thereof.</p>
申请公布号 EP0325063(A1) 申请公布日期 1989.07.26
申请号 EP19880400131 申请日期 1988.01.21
申请人 MERRELL DOW PHARMACEUTICALS INC. 发明人 SCHECHTER, PAUL J.;ORWIN, JOHN M.;HINZE, CHRISTIAN KARL
分类号 C07D211/22;A61K31/445;A61K31/455;A61P25/20 主分类号 C07D211/22
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