发明名称 |
DRUG PREPARATION OF COMPLEX OF POLYRIBOINOSINIC ACID, POLYRIBOCYTIDYLIC ACID AND POLY-L-LYSINE |
摘要 |
PURPOSE:To obtain a freeze-dried drug preparation having improved solubility and stability after the storage over a long period and useful as an antitumor agent, by adding a soluble protein and polysaccharide as constituent components to a polyriboinosinic acid.polyribocytidylic acid.poly-L-lysine complex. CONSTITUTION:A freeze-dried drug preparation composed of a polyriboinosinic acid.polyribocytidylic acid.poly-L-lysine complex is added with a soluble protein and/or polysaccharide as constituent components. The soluble protein is gelatin, collagen or serum albumin or a mixture of two or more of the above proteins. The polysaccharide is dextrin, dextran, chondroitin sulfate or a mixture of two or more of the polysaccharides. The amounts of the soluble protein and the polysaccharide are preferably 0.3-30pts.wt., and 0.1-30pts.wt. per 1pt.wt. of the complex, respectively. |
申请公布号 |
JPH01186818(A) |
申请公布日期 |
1989.07.26 |
申请号 |
JP19880008131 |
申请日期 |
1988.01.18 |
申请人 |
YAMASA SHOYU CO LTD;TOOA EIYOO KK |
发明人 |
NOJIMA SHIGEO;KIMURA TETSUO;MACHIDA HARUHIKO |
分类号 |
A61K31/715;A61K47/00;A61K47/36;A61K47/42;A61P43/00 |
主分类号 |
A61K31/715 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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