CELL GROWTH INHIBITORY FACTOR

摘要

A growth factor designated BCIF and methods for its use are provided. BCIF inhibits proliferation of cells, particularly human breast cancer cells and human melanoma cells. BCIF can be used alone or in combination with other growth factors such as a transforming growth factor-beta or Oncostatin M, which factors may interact additively or synergistically with BCIF to inhibit cell proliferation. Methods for obtaining BCIF are also provided.