发明名称 SUBSTITUTED IMIDAZO(1,5-A)PYRIDINE DERIVATIVES,THE COMPOSITION AND METHOD OF USE THEREOF
摘要 Compounds of the formula <IMAGE> (Ia) wherein R1 represents cyano, nitro or C1-C4-alkyl or the 7,8-dihydro derivative thereof or the 5,6,7,8 tetrahydro derivative of the formula <IMAGE> (Ib) wherein R1 is as defined under formula Ia and R2 is hydrogen, C1-C4-alkyl, halogen etherified or esterified hydroxy or mercapto, carboxy-C1-C4-alkyl or C1-C4-alkoxycarbonyl-C1-C4-alkyl or C1-C4-alkanoyl, to stereoisomers, mixtures of these stereoisomers and salts of these compounds are disclosed as well as their preparation, pharmaceutical compositions containing the same and the use thereof as inhibitors of aromatase activity.
申请公布号 PH23390(A) 申请公布日期 1989.07.26
申请号 PH19270000324 申请日期 1985.06.19
申请人 CIBA-GEIGY AG 发明人 LESLIE JOHNSTON BROWNE
分类号 A61K31/397;A61K31/4184;A61K31/4188;A61K31/435;A61K31/437;A61P5/30;A61P9/12;A61P35/00;A61P43/00;C07D213/55;C07D213/84;C07D233/54;C07D233/61;C07D471/04;C07D487/04;C07F7/10;C07F7/18;C12N9/99 主分类号 A61K31/397
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