发明名称 DIHYDROBENZOFURAN-AND CHROMAN-CARBOXAMIDE DERIVATIVES AND THEIR USE AS NEUROLEPTICS
摘要 The invention relates to new dihydrobenzofuran- and chroman-carboxamide derivatives of the general formula: <IMAGE> (I) in which R and R' are each hydrogen or methyl; n is 1 or 2; m is 1 or 2; Z is either <IMAGE> (a) wherein R1 and R2 are lower alkyl, or <IMAGE> (b) wherein R3 is alkyl, alkenyl, cycloalkyl-alkyl, cycloalkenyl-alkyl, X is H, NH2, methoxy, or methyl and Y is H, Cl, cycloalkylmethylsulfonyl, alkylsulfamoyl or alkylsulfonyl and to their pharmacologically acceptable acid addition salts and their optical isomers, to the processes for the preparation thereof and to the use thereof as medicaments, especially as neuroleptics.
申请公布号 PH23392(A) 申请公布日期 1989.07.26
申请号 PH19860000347 申请日期 1987.01.29
申请人 LABORATOIRES DELAGRANGE 发明人 JACQUELINE FRANCESCHINI;JOSETTE MARGARIT
分类号 C07D307/79;A61K;A61K31/33;A61K31/335;A61K31/34;A61K31/343;A61K31/35;A61K31/352;A61K31/395;A61K31/40;A61K31/4025;A61K33/34;A61K33/40;A61M;A61P25/00;A61P25/08;C07C;C07D;C07D207/00;C07D207/09;C07D307/00;C07D307/77;C07D307/78;C07D307/82;C07D307/84;C07D309/00;C07D311/00;C07D311/04;C07D311/20;C07D311/58;C07D311/74;C07D405/00;C07D405/12;C07D407/00;C07D407/12 主分类号 C07D307/79
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