The present invention relates to a method of potentiating radiation therapy using Co(III) complexes of water soluble, synthetic meso-substituted porphyrins. The method results in the sensitization of both well oxygenated (oxic) and oxygen deficient (hypoxic) tumor cells.
申请公布号
US4851403(A)
申请公布日期
1989.07.25
申请号
US19870041003
申请日期
1987.04.21
申请人
JOHNSON MATTHEY, INC.
发明人
PICKER, DONALD H.;ABRAMS, MICHAEL J.;VOLLANO, JEAN F.;GIANDOMENICO, CHRISTEN M.