摘要 |
There are described compounds of formula I, <IMAGE> I in which A is a benzene or heterocyclic ring, y is 0 or 1, L is a group containing 1 or 2 carbon atoms, or is a single bond, R9 and R10 have a variety of significances, e.g. R10 may form part of a double bond with L, or the group -NR9R10 forms a ring carrying substituents R1 and R8, or when L is a single bond -NR10 and R8 may form a ring carrying substituents R16 to R25, or the group -LNR9R10 forms a heterocyclic ring carrying substituents R26 to R33, R1 to R8 and R16 to R33 have a variety of significances n is 0, 1 or 2, x is 3, 4 or 5, X is S, O or NR15, R15 is hydrogen, -COR, -COOR or alkyl optionally substituted by -OCOR, and certain provisos. Processes for making the compounds and pharmaceutical formulations containing them, e.g. for the treatment of conditions involving excess gastric acid secretion, are also described.
|