发明名称 DERIVES DE (DELTA) 14,29-15-HYDROXY ET 14-HYDROXY-(DELTA)- 15,16-MILBEMYCINE
摘要 <p>Novel lactones for controlling pests of animals and plants Milbemycin derivatives of the formula I (I) wherein A has the structure ¢=.DELTA.14,29-15-ol! or the structure ¢=14-hydroxy-.DELTA.15,16!, X is either -CH(OR1)- or -CO-, R1 is hydrogen, a silyl group or an acyl group, and R2 is methyl, ethyl, isopropyl or sec-butyl, can be prepared by singulett oxygen oxidation of the milbemycin derivatives of the formula II herein, wherein X and R2 have the above meanings, and subsequent reduction of the 15- and 14-peroxides obtained as intermediates. Compounds of the formula I can be prepared as such or in the form of compositions for controlling endo- and ectoparasites, in particular nematodes which are parasites of animals.</p>
申请公布号 CA1257586(A) 申请公布日期 1989.07.18
申请号 CA19840466670 申请日期 1984.10.31
申请人 CIBA-GEIGY AG 发明人 GEHRET, JEAN-CLAUDE
分类号 A01N43/90;A01N;A01N43/24;A01N55/00;A61K31/35;A61K31/355;A61P33/00;C07D;C07D307/00;C07D311/00;C07D313/00;C07D493/22;C07G;C07H19/01;(IPC1-7):A01N43/90 主分类号 A01N43/90
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