摘要 |
<p>Novel lactones for controlling pests of animals and plants Milbemycin derivatives of the formula I (I) wherein A has the structure ¢=.DELTA.14,29-15-ol! or the structure ¢=14-hydroxy-.DELTA.15,16!, X is either -CH(OR1)- or -CO-, R1 is hydrogen, a silyl group or an acyl group, and R2 is methyl, ethyl, isopropyl or sec-butyl, can be prepared by singulett oxygen oxidation of the milbemycin derivatives of the formula II herein, wherein X and R2 have the above meanings, and subsequent reduction of the 15- and 14-peroxides obtained as intermediates. Compounds of the formula I can be prepared as such or in the form of compositions for controlling endo- and ectoparasites, in particular nematodes which are parasites of animals.</p> |