发明名称 |
Phosphinylcycloalkylcarbonyl and phosphinylcycloalkenylcarbonyl dipeptides |
摘要 |
Compounds of the formula <IMAGE> and their pharmaceutically acceptable salts wherein Z completes a cycloalkyl ring, a substituted cycloalkyl ring, a cycloalkenyl ring, a substituted cycloalkenyl ring or a saturated heteroalkyl ring; R2 is lower alkyl, aralkyl or aminoalkyl and X is an amino or imino acid. The compounds possess angiotensin converting enzyme inhibition activity.
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申请公布号 |
US4849525(A) |
申请公布日期 |
1989.07.18 |
申请号 |
US19870098651 |
申请日期 |
1987.09.21 |
申请人 |
E. R. SQUIBB & SONS, INC. |
发明人 |
WELLER, III, HAROLD N.;GORDON, ERIC M. |
分类号 |
A61K38/55;A61K31/675;A61K38/00;A61P9/12;A61P43/00;C07K5/06;C07K5/08;C07K14/81;C12N9/99 |
主分类号 |
A61K38/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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