| 发明名称 |
Allenyl amines |
| 摘要 |
The present invention relates to compounds which are allenyl amines, more specifically, beta -ethenylidene-(substituted)ethanamines, possessing antihypertensive activity. They are prepared by a noval reaction of a protected N,N-bis(trimethylsilyl)-4-methoxy-2-butynylamine compound with a metallo-organic compound, with subsequent removal of the silyl protecting groups to provide the desired compound.
|
| 申请公布号 |
US4847288(A) |
申请公布日期 |
1989.07.11 |
| 申请号 |
US19880153106 |
申请日期 |
1988.02.08 |
| 申请人 |
MERRELL DOW PHARMACEUTICALS INC. |
发明人 |
MCCARTHY, JAMES R.;BARGAR, THOMAS M.;BARNEY, CHARLOTTE L.;MATTHEWS, DONALD P.;BROERSMA, ROBERT J. |
| 分类号 |
C07D213/38;C07D231/12;C07D233/54;C07D277/28;C07D307/52;C07D333/20;C07D333/58 |
主分类号 |
C07D213/38 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
