PHARMACEUTICALLY ACTIVE SALT DERIVATIVE OF 3-HYDROXY -5-(HYDROXYMETHYL)-2-METHYLISONICOTINALDEHYDE PHOSPHATE

摘要

The present invention relates to a novel pharmacologically active salt derivative, constituted by 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxy-phenyl)-1-butanone 3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde-5-phosphate, to the process for the production thereof, and to the related pharmaceutical compositions. Said salt derivative is produced by reacting 3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde-5-phosphoric acid with 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-3-butanone in an organic solvent and subsequently crystallizing the reaction product. Said salt derivative carries out an important pharmacological activity as inhibitor of platelet aggregation with vasodilative action.