| 发明名称 |
Vectors and compounds for expression of zymogen forms of human protein C. |
| 摘要 |
<p>A method for the recombinant production of zymogen forms of human protein C is described. These zymogen forms differ from native zymogen protein C in their increased sensitivity to activation by thrombin and thrombin/thrombomodulin. DNA compounds, vectors, and transformants useful in the method are also disclosed.</p> |
| 申请公布号 |
EP0323149(A2) |
申请公布日期 |
1989.07.05 |
| 申请号 |
EP19880312201 |
申请日期 |
1988.12.22 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
BANG, NILS ULRIK;EHRLICH, HARTMUT JOSEF;GRINNELL, BRIAN WILLIAM;YAN, SAU-CHI BETTY |
| 分类号 |
C12N9/50;A61K31/70;A61K38/43;A61K38/46;A61P7/04;C07H21/04;C07K14/00;C07K14/745;C07K19/00;C12N5/10;C12N9/64;C12N15/09;C12N15/12;C12N15/15;C12R1/91 |
主分类号 |
C12N9/50 |
| 代理机构 |
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