| 摘要 |
Aryl or aroyl ureas and carbamic acid derivatives of formula A-X-NHCW-Y-B and pharmaceutically acceptable salts thereof wherein A is a specified aromatic radical including optionally substituted phenyl X is a direct bond or CO W is O or S Y is NH or S and B is a specified saturated azacyclic ring, eg tropan-3-yl or quinuclidin-3-yl, possess 5-HT3-antagonistic activity and are, for example, useful in treatment of migraine, emesis, anxiety, gastro-intestinal disorders and as anti-psychotics. |
