摘要 |
<p>1-Acyl-2-pyrazoline derivatives represented by the formula <CHEM> where R<1> denotes a hydrogen atom, pyridyl group, pyrazinyl group, alkyl group, aryl group, or alkoxy group; and R<2>, R<3>, and R<4> independently denote a hydrogen atom, furyl group, pyridyl group, alkyl group, or aryl group, are produced by cyclizing by heating an acylhydrazone derivative represented by the formula <CHEM> where R<1>, R<2>, R<3>, and R<4> are defined as above, to produce compounds having useful anti-cerebral edema activity.</p> |