发明名称 |
Oxindole alkaloids having properties stimulating the immunologic system |
摘要 |
Tetra- and pentacyclic oxindole alkaloids, in particular the alloisopteropodine, isomer A, a pentacyclic oxindole alkaloid, are suitable for the unspecific stimulation of the immunologic system, which has been proved by a substantially percental phagocytosis increase in the granulocytic test according to BRANDT (in vitro), a substantial percental increase of the CL-response in the chemiluminescence test (in vitro) and a high increase of the phagocytosis activity of tissue macrophages of the reticoloendothelial system in the carbon-clearence-test (CCT) according to BIOZZI.
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申请公布号 |
US4844901(A) |
申请公布日期 |
1989.07.04 |
申请号 |
US19880195458 |
申请日期 |
1988.05.16 |
申请人 |
KLAUS KEPLINGER |
发明人 |
KEPLINGER, KLAUS;WAGNER, HILDEBERT;KREUTZKAMP, BARBARA |
分类号 |
A61K36/18;A61K31/35;A61K31/40;A61K31/435;A61K36/00;A61K36/062;A61K36/74;C07G99/00 |
主分类号 |
A61K36/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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