| 摘要 |
NEW MATERIAL:The benzamide derivative of formula I (A is group of formula II, formula III, formula IV or formula V; R1 is H, nitro or alkoxy; R2 is alkoxy; R3 is H, nitro, alkoxy or halogen). EXAMPLE:N-[2-(1-pyrrolidino)ethyl]-2-nitro-3,5,6-trimethoxybenzamide. USE:A drug having an action to promoting the motion of digestive tracts of mammals and an antiemetic action. It is expected to be useful in medical field. PREPARATION:The compound of formula I can be produced by reacting a compound of formula VI or its reactive derivative with an amine of formula H-A in a solvent such as tetrahydrofuran in the presence of a condensation agent such as N-N'-dicyclohexylcarbodiimide. |
