| 摘要 |
NEW MATERIAL:A compound expressed by formula I (R<1> and R<2> represent H or OH; X represents COOH, COOR or CH2OH; Y represents H, R or COR; Z represents OH, OR or SR; R represents lower alkyl). USE:An antitumor agent, etc., having superior C-kinase-inhibitory action and cell-growth-inhibitory action. PREPARATION:For example, a compound expressed by formula II is reacted with 1-1.1 equivalent tetraacetate salt at ambient temperature in acetic acid for 7-10hr, and the reaction product is treated with an alcohol expressed by the formula ROH to afford to a compound wherein Z is OR. |
