Composition containing a peptide fragment of platelet factor four and method for restoring suppressed immune responses

摘要

Compositions and methods for modulating immune responses in mammals comprising immunomodulating-effective amounts of PF4 or a biologically active peptide fragment of platelet factor 4 are disclosed herein. Immunomodulation includes one or more aspects of restoration of suppressed immune responses, inhibition of immune suppression (due to exposure of a mammal of an agent that causes suppressor cell activation) and augmentation of normal immune responses.