N-[4-o-hydroxyphenyl-1,3-dioxan-5-ylhexenoyl]sulphonamides

摘要

The invention concerns novel N-[4(Z)-2-substituted-6-(4-o-hydroxyphenyl-1,3 dioxan-cis-5-yl)hexenoyl]sulphonamide derivatives of formula I of value as therapeutic agents. Typically R1 is a branched (3-6C)alkyl, trifluoromethyl or phenyl radical as defined hereinafter and R2 is alkyl, benzyl or phenyl. The invention also discloses salts of the formula I compounds as well as pharmaceutical compositions containing the compounds and processes for the production of the compounds.