| 摘要 |
Preparation of nizatidine (i.e. N-(2-(((2-((dimethylamino) methyl)-4- thiazolyl)methyl)thio)ethyl)-N'-methyl-2-nitro-1,1ethenediamine) of formula (I) comprises reacting 1-alkoxy-Nmethyl-2-nitroetheneamine of formula (II) with 4-(((2-iminoethyl) thio)methyl)-N,N-dimethyl-2- thiazolemethanamine. In formula, R is 1-4C alkyl. Nizatidine of formula (I) is a known antiulcer cpd..
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