发明名称 Prodn. of antiinflammatory 4-naphthyl-2-butanone deriv.
摘要 4-(6-Methoxy-5-Q-2-naphthyl) -4-hydroxy- 3-buten-2-ones of formula (I) and 2-acetyl- 6-methoxy-5 -Q-naphthalenes of formula (II) are new: Q is a protecting gp., esp halogen. Prodn. of 4-(6-methoxy-2-naphthyl) -2-butanone (III) is effected by catalytic hydrogenation of (I) or its Na salts. Pref. hydrogenation is effected at 0-70 deg.C and low or moderate H2 pressure in an inert organic solvent using a Pd catalyst.
申请公布号 CH670631(A5) 申请公布日期 1989.06.30
申请号 CH19870000541 申请日期 1987.02.13
申请人 BEECHAM GROUP PLC 发明人 FARUK, EROL ALI
分类号 B01J23/00;C07B61/00;C07C45/00;C07C45/45;C07C45/46;C07C45/65;C07C49/255;C07C67/00 主分类号 B01J23/00
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