| 发明名称 |
TREATMENT OF MALIGNANT TUMORS WITH 8-CHLOROADENOSINE 3',5'-CYCLIC PHOSPHATE, 8-AMINOADENOSINE 3',5'-CYCLIC PHOSPHATE AND PREPARATION THEREOF |
| 摘要 |
The compounds 8-chloroadenosine 3',5'-cyclic phosphate and 8-aminoadenosine 3',5'-cyclic phosphate are used together or separately to treat malignant tumors in warm blooded animals. Two novel single step syntheses of 8-chloroadenosine 3',5'-cyclic phosphate and other related adenine and adenosine compounds from corresponding adenosine 3',5'-cyclic phosphate and other respective related adenosine compounds are disclosed. |
| 申请公布号 |
WO8905648(A1) |
申请公布日期 |
1989.06.29 |
| 申请号 |
WO1988US01217 |
申请日期 |
1988.04.20 |
| 申请人 |
NUCLEIC ACID RESEARCH INSTITUTE |
发明人 |
ROBINS, ROLAND, K.;REVANKAR, GANAPATHI, R.;CHANG, YU-AN |
| 分类号 |
C07D473/34;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7076;A61P35/00;C07H19/16;C07H19/20;(IPC1-7):A61K31/70 |
主分类号 |
C07D473/34 |
| 代理机构 |
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