| 摘要 |
A nucleotide of the formula [IV] shown below: <IMAGE> [IV] wherein: X is hydrogen or -CO-(CH2)n-CO-R3; each of m and n is an integer up to 20; R0 is a protective group of a phosphoric acid group, R1 is hydrogen or a protective group for a 5'-hydroxyl group, R2 is hydrogen or a protective group for an amino group, R3 is a carrier having an amino group as the functional group and bound at this functional group in this compound, Y is oxygen atom (-0-) or an imino group (-NH-). This nucleotide, when the X is -CO-(CH2)n-CO-R3, has a carrier (R3) through a spacer (-CO-(CH2)m-CO-) on extension from the amino group of deoxycytidine and therefore can be used as the starting material, namely the resin, for synthesizing a 3'-aminated oligonucleotide according to the solid phase method. |
