发明名称 ANTIVIRAL ANTITUMOR ANTIMETASTATIC IMMUNE SYSTEM ENHANCING NUCLEOSIDES AND NUCLEOTIDES
摘要 Compounds of structure (I), wherein R4, R5, R6 and R7 individually are H, OH or C1-C18 O-acyl and R3 is H, C1-C18 acyl or (1); or R5 and R7 are H or OH, R6 is H and together R3 and R4 are (2); and X is =O or =S; Y is -OH, -SH, -NH2 or halogen; and Z is H, -NH2, -OH or halogen; wherein halogen is Cl or Br; or pharmaceutically acceptable salt thereof are useful as antivirals, antitumors, antimetastatics and as immune system enhancers.
申请公布号 WO8905649(A1) 申请公布日期 1989.06.29
申请号 WO1988US02982 申请日期 1988.09.02
申请人 BRIGHAM YOUNG UNIVERSITY 发明人 ROBINS, ROLAND, KENITH;COTTAM, HOWARD, BRINKERHOFF
分类号 A61K31/70;A61K31/7042;A61K31/7052;A61P31/12;A61P35/00;A61P37/04;C07H19/24;(IPC1-7):A61K31/70;C07H19/20 主分类号 A61K31/70
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